The Food and Drug Administration (FDA), once a trusted guardian of public health, now faces criticism for its close ties with Big Pharma, earning nicknames like “Federal Deceit Advocates” and “Federal Drug Atrocities.” This article examines the FDA’s failures, its revolving door with the pharmaceutical industry, and how corporate protectionism has overshadowed public health. With high-profile drug approval failures like the opioid crisis and Vioxx scandal, and financial dependency on pharmaceutical user fees, the FDA’s actions often prioritize corporate profits over public welfare. To restore trust and integrity, significant reforms are necessary, focusing on reducing conflicts of interest and increasing transparency.